Profile
Hi, I'm Xingyu Pan, Estrella online. I'm a postdoctoral researcher in the Pediatric Cancer Metabolism group (Morscher Lab) at the University Children's Hospital Zurich, where I build software and methods for single-cell metabolomics and mass spectrometry, including SCMeTA and LEAF. Before Zurich I did my BSc and PhD in Chemistry at Tsinghua University.
When I'm not at my desk, I'm usually loading a roll of film into a camera somewhere.
cat education.md
- 2024.11 – now
Postdoctoral researcher
University Children's Hospital Zurich
Pediatric Cancer Metabolism · Morscher Lab
- 2018.09 – 2024.06
PhD, Chemistry
Tsinghua University
Department of Chemistry, Beijing
- 2014.09 – 2018.06
BSc, Chemistry
Tsinghua University
Department of Chemistry, Beijing
ls publications/ orcid scholar
2026
- LEAF
Zenodo software · sole author
2025
- A Tandem Cytometry Platform for Single-Cell Analysis of Protein and Metabolites
Analytical Chemistry 97(13), 6962–6966
- High-throughput single-cell metabolites profiling reveals metabolic reprogramming confers cisplatin resistance in lung cancer
Talanta 285, 127355
2024
- SCMeTA: a pipeline for single-cell metabolic analysis data processing
Bioinformatics 40(9), btae545 first author
- High-Throughput Metabolite Analysis of Unicellular Microalgae by Orthogonal Hybrid Ionization Label-Free Mass Cytometry
Analytical Chemistry 96(28), 11404–11411
- Single-Cell Unsaturated Lipid Profiling for Studying Chemoresistance Heterogeneity of Triple-Negative Breast Cancer Cells
Analytical Chemistry
- Single-cell metabolite profiling enables information-rich classification of lymphocyte types and subtypes
Chemical Communications 60(4), 392–395
2022
- Recent progress in mass spectrometry for single-cell metabolomics
Current Opinion in Chemical Biology 71, 102226 review · first author
- The heterogeneity of oxidized lipids in individual tumor cells reveals NK cell-mediated cytotoxicity by label-free mass cytometry
Analyst 147(24), 5754–5763
- Dynamic metabolic change of cancer cells induced by natural killer cells at the single-cell level studied by label-free mass cytometry
Chemical Science 13(6), 1641–1647
- Rapid quantitative analysis of hormones in serum by multilayer paper spray MS: Free MS from HPLC
Talanta 237, 122900
2021
- Site-Specific Scissors Based on Myeloperoxidase for Phosphorothioate DNA
Journal of the American Chemical Society 143(31), 12361–12368
- Discriminating Leukemia Cellular Heterogeneity and Screening Metabolite Biomarker Candidates using Label-Free Mass Cytometry
Analytical Chemistry 93(29), 10282–10291
2019
- Label-free Mass Cytometry for Unveiling Cellular Metabolic Heterogeneity
Analytical Chemistry 91(15), 9777–9783
- Chemical-Modified Nucleotide-Based Elemental Tags for High-Sensitive Immunoassay
Analytical Chemistry 91(9), 5980–5986
2018
- Combination of Droplet Extraction and Pico-ESI-MS Allows the Identification of Metabolites from Single Cancer Cells
Analytical Chemistry 90(16), 9897–9903
cat skills.txt
languages
- Python
- TypeScript / JavaScript
- R
- Rust
- SQL
tools & frameworks
- Vue 3 / Astro
- FastAPI / Pydantic
- Bioinformatics pipelines
- Docker / Nix
- PostgreSQL / DuckDB
domains
- Computational biology
- Metabolomics
- Single-cell analysis
- Data visualization
- Film photography
cat contact.json
{
"email": "estrellaxd05@gmail.com",
"orcid": "https://orcid.org/0009-0002-6704-2224",
"scholar": "https://scholar.google.com/citations?user=A4pL4bsAAAAJ",
"github": "https://github.com/EstrellaXD",
"blog": "https://blog.estrella.cloud"
} echo $STATUS
[ok] available for collaboration and interesting projects